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C.A. Campbell, O. Fursova, X. Cheng, E. Snella, A. McCune, L. Li, B. Solchenberger, B. Schmid, D. Sahoo, M. Morton, D. Traver, R. Espin-Palazon, A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation, Blood Adv 5(3) (2021) 796-811 https://doi.org/10.1182/bloodadvances.2020003096

M. Winterhoff, F. Chen, N. Sahini, T. Ebensen, M. Kuhn, V. Kaever, H. Bahre, F. Pessler, Establishment, Validation, and Initial Application of a Sensitive LC-MS/MS Assay for Quantification of the Naturally Occurring Isomers Itaconate, Mesaconate, and Citraconate, Metabolites 11(5) (2021) https://doi.org/10.3390/metabo11050270

A. Gengatharan, S. Malvaut, A. Marymonchyk, M. Ghareghani, M. Snapyan, J. Fischer-Sternjak, J. Ninkovic, M. Gotz, A. Saghatelyan, Adult neural stem cell activation in mice is regulated by the day/night cycle and intracellular calcium dynamics, Cell 184(3) (2021) 709-722 e13 https://doi.org/10.1016/j.cell.2020.12.026

M. Schonung, J. Hess, P. Bawidamann, S. Stable, J. Hey, J. Langstein, Y. Assenov, D. Weichenhan, P. Lutsik, D.B. Lipka, AmpliconDesign - an interactive web server for the design of high-throughput targeted DNA methylation assays, Epigenetics  (2020) https://doi.org/10.1080/15592294.2020.1834921

L. Zorro Shahidian, M. Haas, S. Le Gras, S. Nitsch, A. Mourao, A. Geerlof, R. Margueron, J. Michaelis, S. Daujat, R. Schneider, Succinylation of H3K122 destabilizes nucleosomes and enhances transcription, EMBO Rep 22(3) (2021) e51009. https://doi.org/10.15252/embr.202051009

R. Karlina, D. Lutter, V. Miok, D. Fischer, I. Altun, T. Schottl, K. Schorpp, A. Israel, C. Cero, J.W. Johnson, I. Kapser-Fischer, A. Bottcher, S. Keipert, A. Feuchtinger, E. Graf, T. Strom, A. Walch, H. Lickert, T. Walzthoeni, M. Heinig, F.J. Theis, C. Garcia-Caceres, A.M. Cypess, S. Ussar, Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice, Life Sci Alliance 4(1) (2021) https://doi.org/10.26508/lsa.202000924

S. Bilekova, S. Sachs, H. Lickert, Pharmacological Targeting of Endoplasmic Reticulum Stress in Pancreatic Beta Cells, Trends Pharmacol Sci 42(2) (2021) 85-95 https://doi.org/10.1016/j.tips.2020.11.011

L.H.Y. Lau, J. Nano, A. Cecil, F. Schederecker, W. Rathmann, C. Prehn, T. Zeller, A. Lechner, J. Adamski, A. Peters, B. Thorand, Cross-sectional and prospective relationships of endogenous progestogens and estrogens with glucose metabolism in men and women: a KORA F4/FF4 Study, BMJ Open Diabetes Res Care 9(1) (2021) https://doi.org/10.1136/bmjdrc-2020-001951

L. Keane, I. Antignano, S.P. Riechers, R. Zollinger, A.A. Dumas, N. Offermann, M.E. Bernis, J. Russ, F. Graelmann, P.N. McCormick, J. Esser, D. Tejera, A. Nagano, J. Wang, C. Chelala, Y. Biederbick, A. Halle, P. Salomoni, M.T. Heneka, M. Capasso, mTOR-dependent translation amplifies microglia priming in aging mice, J Clin Invest 131(1) (2021) https://doi.org/10.1172/JCI132727

T. A. Bedrosian, J. Houtman, J. S. Eguigure, S. Ghassemzadeh, N. Rund, N. M. Novaresi, L. Hu, S. L. Parylak , A. M. Denli, L. Randolph-Moore, T. Namba, F. H. Gage, T. Toda. Lamin B1decline underlies age-related loss of adult hippocampal neurogenesis. EMBO J. Dec 2020 doi.org/10.15252/embj.2020105819

T. Conlon, G. John-Schuster, D. Heide, D. Pfister, M. Lehmann, Y. Hu, Z. Ertüz, M. Lopez, M. Ansari, M. Strunz, C. Mayr, C. Ciminieri, R. Costa, M. Kohlhepp, A. Guillot, G. Günes, A. Jeridi, M. Funk, G. Beroshvili, S. Prokosch,  J. Hetzer, S. Verleden, H. Alsafadi, M. Lindner, G. Burgstaller, L. Becker, M. Irmler, M. Dudek, J. Janzen, E. Goffin, R. Gosens, P. Knolle, B. Pirotte, T. Stoeger, J. Beckers, D. Wagner, I. Singh, F. Theis, M. Hrabé de Angelis, T. O’Connor, F. Tacke, M. Boutros, E. Dejardin, O. Eickelberg, H. Schiller, M. Königshoff, M. Heikenwalder, A. Yildirim. Inhibition of LTßR signalling activates WNT-induced regeneration in lung. Nature. Nov 2020. doi.org/10.1038/s41586-020-2882-8

P. Morigny, J. Zuber, M. Haid, D. Kaltenecker, F. Riols, J. Lima, E. Simoes, J. Pinhata Otoch, S. Fisker Schmidt, S. Herzig, J. Adamski, M. Seelaender, M. Berriel Diaz, M. Rohm. High levels of modified ceramides are a definingfeature of murine and human cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle. Oct 2020. doi.org/10.1002/jcsm.12626

S. Ahmed, J. Maldera, D. Krunic, G. Paiva-Silva, C. Pénalva, A. Teleman, B. Edgar. Fitness trade-offs incurred by ovary-to-gut steroid signaling in Drosophila. Nature. Aug 2020. doi.org/10.1038/s41586-020-2462-y

F. Bertan, L. Wischhof, L. Sosulina, M. Mittag, D. Dalügge, A. Fornarelli, F. Gardoni, E. Marcello, M. Di Luca, M. Fuhrmann, S. Remy, D. Bano, P. Nicotera. Loss of Ryanodine Receptor 2 impairs neuronal activity-dependent remodeling of dendritic spines and triggers compensatory neuronal hyperexcitability. Cell Death & Differentiation June 2020. doi.org/10.1038/s41418-020-0584-2

M. Funk, J. Zhou, and M. Boutros. Ageing, Metabolism and the Intestine. EMBO reports June 2020. doi.org/10.15252/embr.202050047

F. Köhler, F. Bormann, G. Raddatz, J. Gutekunst, S. Corless, T. Musch, A. Lonsdorf, S. Erhardt, F. Lyko, and M. Rodríguez-Paredes. Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilfordprogeria syndrome. Genome Medicine May 2020. doi.org/10.1186/s13073-020-00749-y

P. Bheda, D. Aguilar-Gómez, N. Becker, J. Becker, E. Stavrou, I. Kukhtevich, T. Höfer, S. Maerkl, G. Charvin, C. Marr, A. Kirmizis, R. Schneider. Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory. Molecular Cell May 2020. doi.org/10.1016/j.molcel.2020.04.016

P. Mahaddalkar, K. Scheibner, S. Pfluger, Ansarullah, M. Sterr, J. Beckenbauer, M. Irmler, J. Beckers, S. Knöbel, and H. Lickert. Generation of pancreatic β cells from CD177⁺ anterior definitive endoderm. Nature Biotech Apr 2020. doi.org/10.1038/s41587-020-0492-5

L. Solé-Boldo, G. Raddatz, S. Schütz, J.-Ph. Mallm, K. Rippe, A. Lonsdorf, M. Rodríguez-Paredes, and F. Lyko. Single-cell transcriptomes of the human skin revealage-related loss offibroblast priming. Nature Comm Bio Apr 2020. doi.org/10.1038/s42003-020-0922-4

F. Schederecker, A. Cecil, C. Prehn, J. Nano, W. Koenig, J. Adamski, T. Zeller, A. Peters and B. Thorand. Sex hormone-binding globulin, androgens and mortality: the KORA-F4 cohort study. Endocr Connect Apr 2020. doi.org/10.1530/EC-20-0080

P. Bheda. Metabolic transcriptional memory. Mol Metabol Mar 2020. doi.org/10.1016/j.molmet.2020.01.019

C. Huth, A. Bauer, A. Zierer, J. Sudduth-Klinger, C. Meisinger, M. Roden, A. Peters, W. Koenig, C. Herder, and B. Thorand. Biomarker-defined pathways for incident type 2 diabetes and coronary heart disease-a comparison in the MONICA/KORA study. Cardiovasc Diabetol Mar 2020. doi.org/10.1186/s12933-020-01003-w.

V. Ignatova, P. Stolz, S. Kaiser, T. Gustafsson, P.R. Lastres, A. Sanz-Moreno, Y. Cho, O. Amarie, A. Aguilar-Pimentel, T. Klein-Rodewald, J. Calzada-Wack, L. Becker, S. Marschall, M. Kraiger, L. Garrett, C. Seisenberger, S. Hölter, K. Borland, E. van de Logt, P. Jansen, M. Baltissen, M. Valenta, M. Vermeulen, W. Wurst, V. Gailus-Durner, H. Fuchs, M. Hrabe de Angelis, O. Rando, S. Kellner, S. Bultmann, and R. Schneider. The rRNA m⁶A methyltransferase METTL5 is involved in pluripotency and developmental programs. Genes Dev Mar 2020. doi.org/10.1101/gad.333369.119

I. Ansari, G. Raddatz, J. Gutekunst, M. Ridnik, D. Cohen, M. Abu-Remaileh, T. Tuganbaev, H. Shapiro, E. Pikarsky, E. Elinav, F. Lyko, and Y. Bergman. The microbiota programs DNA methylation to control intestinal homeostasis and inflammation. Nature Microbiology Mar 2020. doi.org/10.1038/s41564-019-0659-3

S. Sachs, A. Bastidas-Ponce, S. Tritschler, M. Bakhti, A. Böttcher, M. Sánchez-Garrido, M. Tarquis-Medina, M. Kleinert, K. Fischer, S. Jall, A. Harger, E. Bader, S. Roscioni, S. Ussar, A. Feuchtinger, B. Yesildag, A. Neelakandhan, C. Jensen, M. Cornu, B. Yang, B. Finan, R. DiMarchi, M. Tschöp, F. Theis, S. Hofmann, T. Müller, and H. Lickert. Targeted pharmacological therapy restores β-cell
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A. Vogl, L. Phu, R. Becerra, S. Giusti, E. Verschueren, T. Hinkle, M. Bordenave, M. Adrian, A. Heidersbach, P. Yankilevich, F. Stefani, W. Wurst, C. Hoogenraad, D. Kirkpatrick, D. Refojo, and M. Sheng. Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics. Nat Struct Mol Biol Feb 2020. doi.org/10.1038/s41594-019-0370-3

I. Bellantuono, R. de Cabo, D. Ehninger, C. Di Germanio, A. Lawrie, J. Miller, S. J. Mitchell, I. Navas-Enamorado, P. K. Potter, T. Tchkonia, J. L. Trejo, and D. W. Lamming. A toolbox for the longitudinal assessment of healthspan in aging mice. Nature Protocols. Feb 2020. doi.org/10.1038/s41596-019-0256-1

V. Katzke, T. Johnson, D. Sookthai, A. Hüsing, T. Kühn, and R. Kaaks. Circulating liver enzymes and risks of chronic diseases and mortality in the prospective EPIC-Heidelberg case-cohortstudy. BMJ Open Jan 2020. doi.org/10.1136/bmjopen-2019-033532

Fangfang Chen, Peer Lukat, Azeem Ahmed Iqbal, Kyrill Saile, Volkhard Kaever, Joop van den Heuvel, Wulf Blankenfeldt, Konrad Büssow, and Frank Pessler. Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconitate synthesis. Proceedings of the National Academy of Sciences. 2019. doi.org/10.1073/pnas.1908770116

Tilman Kühn, Magdalena Stepien, Marina López-Nogueroles, Antje Damms-Machado, Disorn Sookthai, Theron Johnson, Marta Roca, Anika Hüsing, Sandra González Maldonado, Amanda J. Cross, Neil Murphy, Heinz Freisling, Sabina Rinaldi, Augustin Scalbert, Veronika Fedirko, Gianluca Severi, Marie-Christine Boutron-Ruault, Francesca Romana Mancini, Solomon A Sowah, Heiner Boeing, Paula Jakszyn, Maria J Sánchez, Susana Merino, Sandra Colorado-Yohar, Aurelio Barricarte, Kay Tee Khaw, Julie A. Schmidt, Aurora Perez-Cornago, Antonia Trichopoulou, Anna Karakatsani, Paschalis Thriskos, Domenico Palli, Claudia Agnoli, Rosario Tumino, Carlotta Sacerdote, Salvatore Panico, Bas Bueno-de-Mesquita, Carla H. van Gils, Alicia K Heath, Marc J. Gunter, Elio Riboli, Agustín Lahoz, Mazda Jenab, Rudolf Kaaks. Pre-diagnostic plasma bile acid levels and colon cancer risk: A prospective study. Journal of the National Cancer Institute. 2019. doi.org/10.1093/jnci/djz166

Katarina Klepac , Anastasia Georgiadi, Matthias Tschöp, and Stephan Herzig. The role of brown and beige adipose tissue in glycaemic control. Molecular Aspects of Medicine. 2019. doi.org/10.1016/j.mam.2019.07.001

Natalie Krahmer and Matthias Mann. Catching Lipid Droplet Contacts by Proteomics. SAGE Contact. 2019. doi.org/10.1177/2515256419859186

Katarzyna Placek, Joachim L. Schultze, and Anna C. Aschenbrenner. Epigenetic reprogramming of immune cells in injury, repair, and resolution. The Journal of Clinical Investigation. 2019. doi.org/10.1172/JCI124619

Kevin Y. Lee, Quyen Luong, Rita Sharma, Jonathan M. Dreyfuss, Siegfried Ussar, and Ronald Kahn. Developmental and functional heterogeneity of white adipocytes within a single fat depot. EMBO Journal. 2019. doi.org/10.15252/embj.201899291

Llorenç Solé-Boldo, Günter Raddatz, Sabrina Schütz, Jan-Philipp Mallm, Karsten Rippe, Anke S. Lonsdorf, View ORCID ProfileManuel Rodríguez-Paredes, and Frank Lyko. Single-cell transcriptomes of the aging human skin reveal loss of fibroblast priming. bioRxiv. 2019. doi.org/10.1101/633131

Carolina Ballester-López, Thomas M. Conlon, Zeynep Ertüz, Flavia R. Greiffo, Martin Irmler, Stijn E. Verleden, Johannes Beckers, Isis E. Fernandez, Oliver Eickelberg, and Ali Önder Yildirim. The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease. EBiomedicine. 2019. doi.org/10.1016/j.ebiom.2019.03.054

Marius Vital, Tatjana Rud, Silke Rath, Dietmar H. Pieper, and Dirk Schlüter. Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut. Computational and Structural Biotechnology Journal. 2019. https://doi.org/10.1016/j.csbj.2019.07.012

Parthive H. Patel, Clothilde Pénalva, Michael Kardorff, Marianne Roca, Bojana Pavlović, Anja Thiel, Aurelio A. Teleman and Bruce A. Edgar. Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut. Nature Communications. 2019. doi.org/10.1038/s41467-019-12336-w

Lisa Schlicker, Hanny Boers, Christian-Alexander Dudek, Gang Zhao, Arnab Barua, Jean-Pierre Trezzi, Michael Meyer-Hermann, Doris M. Jacobs, and Karsten Hiller. Postprandial Metabolic Effects of Fiber Mixes Revealed by in vivo Stable Isotope Labeling in Humans. Metabolites. 2019. doi.org/10.3390/metabo9050091.

Georgios Kalamakis, Daniel Brüne, Srikanth Ravichandran, Jan Bolz, Wenqiang Fan, Frederik Ziebell, Thomas Stiehl, Francisco Catalá-Martinez, Janina Kupke, Sheng Zhao, Enric Llorens-Bobadilla, Katharina Bauer, Stefanie Limpert, Birgit Berger, Urs Christen, Peter Schmezer, Jan Philipp Mallm, Benedikt Berninger,  Simon Anders, Antonio del Sol, Anna Marciniak-Czochra, Ana Martin-Villalba. Quiescence modulates stem cell maintenance and regenerative capacity in the aging brain. Cell. 2019. doi.org/10.1016/j.cell.2019.01.040.

Florian Koehler, Felix Bormann, Guenter Raddatz, Julian Gutekunst, Tanja Musch, Frank Lyko, Manuel Rodriguez-Paredes. Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome. bioRxiv. 2019. doi.org/10.1101/520403.

Anna Gioran, Antonia Piazzesi, Fabio Bertan, Jonas Schroer, Lena Wischhof, Pierluigi Nicotera, Daniele Bano. Multi-omics identify xanthine as a pro-survival metabolite for nematodes with mitochondrial dysfunction. The EMBO Journal. 2019. doi.org/10.15252/embj.201899558

Daniele Bano, Jochen H. M. Prehn. Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer. EBioMedicine. 2018. doi.org/10.1016/j.ebiom.2018.03.016

Stefan Dehmel, Petra Nathan, Sabine Bartel, Natalia El-Merhie, Hagen Scherb, Katrin Milger, Gerrit John-Schuster, Ali Oender Yildirim, Machteld Hylkema, Martin Irmler, Johannes Beckers, Bianca Schaub, Oliver Eickelberg, Susanne Krauss-Etschmann. Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner. Scientific Reports. 2018. doi.org/10.1038/s41598-018-25762-5

Miriam Hoene, Martin Irmler , Johannes Beckers, Martin Hrabe de Angelis , Hans-Ulrich Häring, Cora Weigert: A Vitamin E-Enriched Antioxidant Diet Interferes with the Acute Adaptation of the Liver to Physical Exercise in Mice. Nutrients. 2018. doi.org/10.3390/nu10050547

David Hoerl, Fabio Rojas Rusak, Friedrich Preusser, Paul Tillberg , Nadine Randel , Raghav K. Chhetri, Albert Cardona, Philipp K. Keller, Hartmann Harz, Heinrich Leonhardt, Mathias Treier, Stephan Preibisch: BigStitcher: Reconstructing high resolution image datasets of cleared and expanded samples. bioRxiv. 2018. doi.org/10.1101/343954.

Michael Meyer-Hermann, Sebastian C. Binder, Luka Mesin, Gabriel D. Victora. Computer Simulation of Multi-Color Brainbow Staining and Clonal Evolution of B Cells in Germinal Centers. Front. Immunol. 2018. doi.org/10.3389/fimmu.2018.02020

Ghazal Montaseri, Alessandro Boianelli, Esteban A. Hernandez-Vargas, Michael Meyer-Hermann. PK/PD-based adaptive tailoring of oseltamivir doses to treat within-host influenza viral infections. Prog Biophys Mol Biol. 2018. doi.org.10.1016/j.pbiomolbio.2018.07.007

Alexandra Moraru, Janica Wiederstein, Daniel Pfaff, Thomas Fleming, Aubry K. Miller, Peter Nawroth, Aurelio A. Teleman. Elevated Levels of the Reactive Metabolite Methylglyoxal Recapitulate Progression of Type 2 Diabetes. Cell Metabolism. 2018. doi.org/10.1016/j.pbiomolbio.2018.07.007

Anna Nieborak, Robert Schneider. Metabolic intermediates – cellular messengers talking to chromatin modifiers. Mol Metab. 2018. doi.org/10.1016/j.molmet.2018.01.007

Brandon L. Pearson, Leonie P. Posselt, Kristin S. Henzel, Dan Ehninger. Limited efficacy of somatic cell lysis buffer to purify laboratory mouse sperm. Epigenomics. 2018. doi.org/10.2217/epi-2018-0015

Silke Rath, Tatjana Rud, André Karch, Dietmar Helmut Pieper and Marius Vital. Pathogenic functions of host microbiota. Microbiome. 2018. doi.org/10.1186/s40168-018-0542-0

Aygul Subkhangulova, Anna R. Malik, Guido Hermey, Oliver Popp, Gunnar Dittmar, Thomas Rathjen, Matthew N. Poy, Alexander Stumpf, Prateep Sanker Beed, Dietmar Schmitz, Tilman Breiderhoff, Thomas E. Willnow. SORCS1 and SORCS3 control energy balance and orexigenic peptide production. EMBO Rep. 2018. doi.org/10.15252/embr.201744810

Lisa Suwandhi, Simone Hausmann, Alexander Braun, Tim Gruber, Silke S. Heinzmann, Eric J. C. Gálvez, Achim Buck, Beata Legutko, Andreas Israel, Annette Feuchtinger, Elizabeth Haythorne, Harald Staiger, Martin Heni, Hans-Ulrich Häring, Philippe Schmitt-Kopplin, Axel Walch, Cristina García Cáceres, Matthias H. Tschöp, Guy A. Rutter, Till Strowig, Martin Elsner, Siegfried Ussar. Chronic D-serine supplementation impairs insulin secretion. Molecular Metabolism. 2018. doi.org/10.1016/j.molmet.2018.07.002

Marius Vital, Adina Howe, Nathalie Bergeron, Ronald M. Krauss, Janet K. Jansson, James M. Tiedje. Metagenomic insights into the degradation of resistant starch by human gut microbiota. Appl Environ Microbiol. 2018. doi.org/10.1128/AEM.01562-18

Xianming Wang, Michael Sterr, Ingo Burtscher, Shen Chen, Anja Hieronimus, Fausto Machicao, Harald Staiger, Hans-Ulrich Häring, Gabriele Lederer, Thomas Meitinger, Filippo M. Cernilogar, Gunnar Schotta, Martin Irmler, Johannes Beckers, Martin Hrabě de Angelis, Michael Ray, Christopher V.E. Wright, Mostafa Bakhti, Heiko Lickert. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Molecular Metabolism. 2018. doi.org/10.1016/j.molmet.2018.01.011.

Lena Wischhof, Anna Gioran, Dagmar Sonntag-Bensch, Antonia Piazzesi, Miriam Stork, Pierluigi Nicotera, Daniele Bano. A disease-associated Aifm1 variant induces severe myopathy in knockin mice. Molecular Metabolism. 2018. doi.org/10.1016/j.molmet.2018.05.002

Kan Xie, Devon P. Ryan, Brandon L. Pearson, Kristin S. Henzel, Frauke Neff, Ramon O. Vidal, Magali Hennion, Isabelle Lehmann, Melvin Schleif, Susanne Schröder, Thure Adler, Birgit Rathkolb, Jan Rozman, Anna-Lena Schütz, Cornelia Prehn, Michel E. Mickael, Marco Weiergräber, Jerzy Adamski, Dirk H. Busch, Gerhard Ehninger, Anna Matynia, Walker S. Jackson, Eckhard Wolf, Helmut Fuchs, Valerie Gailus-Durner, Stefan Bonn, Martin Hrab
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Xianming Wang, Michael Sterr, Ingo Burtscher, Shen Chen, Anja Hieronimus, Fausto Machicao, Harald Staiger, Hans-Ulrich Häring, Gabriele Lederer, Thomas Meitinger, Filippo M. Cernilogar, Gunnar Schotta, Martin Irmler, Johannes Beckers, Martin Hrabě de Angelis, Michael Ray, Christopher V.E. Wright, Mostafa Bakhti, Heiko Lickert. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Molecular Metabolism. 2018. doi.org/10.1016/j.molmet.2018.01.011.

Marius Vital, André Karch, Dietmar H. Pieper. Colonic Butyrate-Producing Communities in Humans: an Overview Using Omics Data. mSystems. 2017. doi.org/10.1128/mSystems.00130-17.

Aging and chronic disease

Metabolic Programming

Inter-organ signaling

Stem cell function

Tissue Maintenance

source: https://www.ncbi.nlm.nih.gov/pubmed/

2017

Garcia-Prat, L. and P. Munoz-Canoves, Aging, metabolism and stem cells: Spotlight on muscle stem cells. Mol Cell Endocrinol, 2017. 445: p. 109-117.

Lushchak, O., et al., The role of the TOR pathway in mediating the link between nutrition and longevity. Mech Ageing Dev, 2017.

Man, K., V.I. Kutyavin, and A. Chawla, Tissue Immunometabolism: Development, Physiology, and Pathobiology. Cell Metab, 2017. 25(1): p. 11-26.

Sharma, U. and O.J. Rando, Metabolic Inputs into the Epigenome. Cell Metab, 2017. 25(3): p. 544-558.

Stout, M.B., et al., Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty. Physiology (Bethesda), 2017. 32(1): p. 9-19.

Vaiserman, A.M., A.K. Koliada, and F. Marotta, Gut microbiota: A player in aging and a target for anti-aging intervention. Ageing Res Rev, 2017. 35: p. 36-45.  

2016

Bonner-Weir, S. and C. Aguayo-Mazzucato, Physiology: Pancreatic beta-cell heterogeneity revisited. Nature, 2016. 535(7612): p. 365-6. 

Gruber, J., Z. Yee, and N.S. Tolwinski, Developmental Drift and the Role of Wnt Signaling in Aging. Cancers (Basel), 2016. 8(8).

Holmes, D., Diabetes: beta-cell heterogeneity - key to unlocking islet regeneration. Nat Rev Endocrinol, 2016. 12(9): p. 495.

Kapahi, P., M. Kaeberlein, and M. Hansen, Dietary restriction and lifespan: Lessons from invertebrate models. Ageing Res Rev, 2016.

Peleg, S., et al., The Metabolic Impact on Histone Acetylation and Transcription in Ageing. Trends Biochem Sci, 2016. 41(8): p. 700-11.  

2015

Fleming, T. and P.P. Nawroth, Reactive metabolites as a cause of late diabetic complications. Biochem Soc Trans, 2014. 42(2): p. 439-42.   014. 63(10): p. 1238-49. 

Marg, A., et al., Human satellite cells have regenerative capacity and are genetically manipulable. J Clin Invest, 2014. 124(10): p. 4257-65.

Longo, V.D. and M.P. Mattson, Fasting: molecular mechanisms and clinical applications. Cell Metab, 2014. 19(2): p. 181-92.

Solon-Biet, S.M., et al., The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice. Cell Metab, 2014. 19(3): p. 418-30.

older

Ribaric, S., Diet and aging. Oxid Med Cell Longev, 2012. 2012: p. 741468.

Liu, H., et al., Augmented Wnt signaling in a mammalian model of accelerated aging. Science, 2007. 317(5839): p. 803-6.