Most chronic diseases such as diabetes, cancer, cardiovascular, respiratory and neurodegenerative diseases as well as chronic infections increase in incidence with age. This indicates common age-related mechanisms acting jointly. Due to increasing life expectancy throughout the world, those age-related diseases are emerging as a growing challenge for patients, doctors, the healthcare system and society as a whole.

Among other things, the AMPro consortium is seeking out new preventive and therapeutic approaches that have a positive effect on metabolic processes. This should enable the innovative and consistent treatment of age-related diseases. The following key aspects of metabolic processes associated with aging will be investigated.

Metabolic pre- and reprogramming 
Prenatal and postnatal mechanisms of metabolic programming at the genetic and epigenetic levels

Inter-organ signaling
Mechanisms of organ and tissue communication

Stem cell function and tissue maintenance 
Tissue and cellular repair mechanisms

The long-term goal is to improve health in an aging society. AMPro creates ideal conditions for successfully tackling one of the most pressing issues in today's society and meeting the challenges of age-related diseases.